Market Overview: The global market size for peptide synthesis reached USD 594 million in 2022 and is projected to achieve USD 1187.41 million by 2032, with a compound annual growth rate (CAGR) of 8% during the forecast period. The increasing prevalence of chronic diseases such as cancer, diabetes, and cardiovascular diseases is a significant driver for the growth in market revenue. The pharmaceutical sector's focus on developing innovative therapeutics utilizing peptides, known for their enhanced efficacy, high selectivity, and low toxicity compared to conventional small-molecule medications, contributes to this trend.

Furthermore, the rising demand for peptide therapies in treating cancer, orphan illnesses, and uncommon diseases is fueling market growth. Increased research and development spending by pharmaceutical and biotechnology companies, aiming to create novel peptides and peptide-based medicines, is expected to further boost market revenue. Peptide therapies are anticipated to gain broader application in treating viral diseases, metabolic disorders, and central nervous system disorders. Innovations in peptide synthesis instruments and technology are additional factors driving market expansion, with automated peptide synthesizers and solid-phase peptide synthesis methods making production more efficient and cost-effective.

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The market is also witnessing growth due to the escalating demand for customized peptides in diagnostic and research applications. The need for bespoke peptides is driven by the rising demand for companion diagnostics and tailored medication. Strict regulations from regulatory bodies such as the Food and Drug Administration (FDA) and Eco-Management and Audit Scheme (EMA) regarding the safety and efficacy of peptide-based pharmaceuticals are contributing to market growth. The implementation of Good Manufacturing Practices (GMP) and Quality-by-Design (QbD) techniques underscores the increasing focus on quality control and assurance in peptide synthesis.

Key Market Segments: Type Outlook: The global peptide synthesis market is segmented into Solid Phase Peptide Synthesis (SPPS), Liquid Phase Peptide Synthesis (LPPS), Hybrid Phase Peptide Synthesis (HPPS), and others. SPPS is anticipated to account for the largest revenue share during the forecast period, driven by its high efficiency and ability to produce high-purity and high-yield peptides. The automation of SPPS significantly reduces peptide synthesis time and costs.

Application Outlook: The global peptide synthesis market is segmented into therapeutics, research, and others. The therapeutic segment is expected to dominate in terms of revenue share, driven by the increasing popularity of peptides in developing potential cures for various ailments. Peptides are particularly relevant in the treatment of diseases such as cancer, diabetes, cardiovascular disease, and neurological problems. The use of peptides in therapeutics is anticipated to grow significantly with advancements in peptide synthesis technology and increased research in this field.

Regional Outlook:

• North America is projected to hold the largest revenue share, driven by the presence of multiple pharmaceutical companies, extensive research and development activities, and a growing demand for peptide treatments. The U.S. alone contributes significantly to global peptide market share, with approximately 2,000 clinical trials involving peptides, according to the National Institutes of Health.
• Asia Pacific is expected to witness the fastest revenue growth, fueled by increasing investments in Peptide Therapeutics and a growing preference for personalized medication. The region is poised for substantial growth in biopharmaceuticals, with an estimated market value of USD 400 billion by 2025, as per the International Trade Administration. Significant investments in biotech and life sciences by countries like China, Japan, and India are driving the demand for peptide synthesis.
• Europe is expected to register a steady revenue growth rate, propelled by the rising prevalence of chronic diseases and the increasing demand for peptide-based medications. The region boasts some of the top peptide synthesis companies globally and has a well-established pharmaceutical industry. The emphasis on customized medicine and targeted medicines is expected to drive the demand for peptide synthesis in Europe.

Major Companies and Competitive Landscape: The global peptide synthesis market is highly competitive, with key players employing various strategies such as mergers and acquisitions, product development, and strategic agreements and contracts to maintain and enhance their market share. Some major companies in the market include Bachem Holding AG, Creative Peptides LLC, Genscript Biotech Corporation, Gyros Protein Technologies AB, Mimotopes Pty Ltd, Thermo Fisher Scientific Inc., Nova Biochem GmbH, Abzena PLC, Anaspec, Inc., and New England Peptide, Inc.

Strategic Developments:

• In 2021, Thermo Fisher Scientific Inc. acquired PPD, a leading contract research organization, for USD 17.4 billion, aiming to expand capabilities in clinical research and development, including peptide synthesis services.
• Gyros Protein Technologies AB collaborated with Selexis SA in 2021 to develop a high-throughput peptide synthesis platform for therapeutic peptides.
• In 2020, Bachem Holding AG acquired American Peptide Company (APC) to expand product offerings and manufacturing capabilities.
• Various other companies, including Bachem, Creative Peptides, and Thermo Fisher Scientific, have introduced new lines of peptide synthesis reagents and services, showcasing advancements and innovation in the field.

Segments Covered in Report: This report provides historical data and forecasts revenue growth at a global, regional, and country level, with an analysis of market trends from 2019 to 2032. The global peptide synthesis market is segmented based on type, application, and region.

Type Outlook (Revenue, USD Million; 2019-2032):

• Solid Phase Peptide Synthesis
• Liquid Phase Peptide Synthesis
• Hybrid Phase Peptide Synthesis
• Others

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