Scientists have used animals to model human diseases for over a hundred years. Mice are particularly useful for this because they share many of the same biological traits as humans and have over 80 percent identical genetic components to humans. A mice model is a laboratory mouse used to study some aspect of human physiology or disease. Various model organisms are used in this regard, but mice are particularly useful because they share mammalian traits with humans and suffer from many of the same diseases. Many mice models have been created to target specific human diseases using selective breeding and genetic engineering. The use of mice models in disease research and research programs has contributed to significant medical breakthroughs. Mice are the model of choice, not only because they are strikingly similar to humans at the genomic level but also because the disease pathophysiology in mice is similar to humans. Mice are an inexpensive and efficient tool to speed up research and drug testing. These features provide researchers with a powerful tool for understanding the mechanisms of human disease and for testing novel drug therapies.

According to our latest study on "Mice Model Market Forecast to 2028 – COVID-19 Impact and Global Analysis – by Type, Service, Technology, Indication, End User, Application, and Mode,” the market is expected to grow from US$ 1,705.70 million in 2022 to US$ 2,340.90 million by 2028; it is estimated to grow at a CAGR of 5.4% from 2022 to 2028. The report highlights trends prevailing in the market and factors governing the market growth. Increased use of mice models in virology, infectious disease, and others; the rising demand for personalized medicine; and increased R&D activities are driving the Mice Model Market. However, the stringent regulations and laws for the ethical use of animals in research are hindering the market growth.

Growing Usage of Mice Models in Virology and Infectious Diseases

Mice models are essential tools to study the pathogenesis of infectious diseases and for the preclinical evaluation of vaccines and therapies against various human pathogens. The use of genetically defined inbred mouse strains, humanized mice, and gene knockout mice has enabled the research community to study the process of the way pathogens cause diseases, the role of specific host genes in controlling or promoting disease, and potential targets for prevention or identification of treatment for a variety of infectious agents. With the emergence of new infectious diseases, the animal model has become a vital tool for studying disease mechanisms and developing therapeutics. Mice with xenografted human immune systems have been used to study the pathogenesis of various infectious agents, including Plasmodium falciparum (malaria), Mycobacterium tuberculosis, dengue virus, and influenza virus. These models have been beneficial for studying HIV, including analyzing viral and host factors that promote viral replication, HIV interactions with the host's immune response, and as platforms for testing therapeutic approaches to control or cure HIV infection. Mice models are an essential resource for studying the mechanisms underlying infectious disease pathogenesis and as platforms for testing potential vaccines and therapies. Mice models are necessary for learning about infections from many human pathogens. They are widely used for preclinical screening of vaccines/therapies because of their high reproducibility, low cost, and ease of experimental manipulation.

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