Protein Expression Market is expected to exceed the market valuation of more than US$ 6 billion by 2027 expanding at a reasonable CAGR of 14% during the forecast period (2021-2027). Protein expression refers to how proteins are synthesized, modified, and regulated in living organisms. The demand for the Protein Expression market is increasing on account of the rising incidence of chronic diseases, growth in the geriatric population, and rising demand for protein biologics. Moreover, the rising demand for therapeutic proteins such as insulin, hormones, monoclonal antibodies, and vaccines also propels market growth. Increasing investment in R&D, by biotechnology and pharmaceutical companies, is another major factor supporting the sector growth.

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The demand for the Protein Expression market is increasing on account of the rising incidence of chronic diseases, growth in the geriatric population, and rising demand for protein biologics. Moreover, the rising demand for therapeutic proteins such as insulin, hormones, monoclonal antibodies, and vaccines also propels market growth. Increasing investment in R&D, by biotechnology and pharmaceutical companies, is another major factor supporting the sector growth.

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Based on Expression Systems, the market is fragmented into Prokaryotic expression systems, Mammalian cell expression systems, Insect cell expression systems, Yeast expression systems, and Other expression systems. The Prokaryotic expression system segment dominated the market in 2020 and is expected to grow at lucrative growth during the forecasted period owing to its large application in biologics and drug productions. Recent progress in recombinant DNA technologies has paved the way to producing recombinant proteins that can be used as therapeutics, vaccines, and diagnostic reagents. Recombinant proteins for these applications are mainly produced using prokaryotic expression systems such as mammalian cells, bacteria, yeast, insect cells, and transgenic plants at laboratory scale as well as in large-scale settings.

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Based on Applications, the market is bifurcated into Therapeutic, Industrial, and Research. The Therapeutic segment dominated the market in 2020 and is expected to grow at lucrative growth during the forecasted period owing to the high demand for therapeutic proteins for the treatment of cancer, infectious diseases, anemia, hemophilia, and multiple sclerosis. Several agents targeting molecules that are crucial both for the tumor and its microenvironment have already been approved by the U.S. Food and Drug Administration for clinical use. The monoclonal antibodies and the small molecule kinase inhibitors constitute two major classes of targeted therapeutic agents, which have different mechanisms of action, toxicity profiles, routes of administration, timing, and dosing.

Based on Products, the market is bifurcated into Reagents, Competent cells, Expression vectors, Services, and Instruments. The Reagents segment dominated the market in 2020 and is expected to grow at lucrative growth during the forecasted period owing to its repetitive purchase for therapeutic, industrial, and research applications. Thermo Fisher Scientific Inc. is the largest player in the protein expression market. The large share of this company can be attributed to its strong suite of expression vectors, reagents, competent cells, and instruments. Owing to its strong sales and distribution network, the company has a significant global footprint.

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For a better understanding of the market adoption of Protein Expression, the market is analyzed based on its worldwide presence in the countries such as North America (United States, Canada, and the Rest of North America), Europe (Germany, France, Spain, United Kingdom and Rest of Europe), Asia-Pacific (China, Japan, India, Australia, and Rest of APAC), and Rest of World. North America will dominate the Protein Expression market on account of the presence of many biopharmaceutical and biotechnology companies in this region. Some of the major players operating in the market include Thermo Fisher Scientific Inc., Merck KGaA, GenScript Biotech Corporation, Agilent Technologies Inc., Takara Bio, Inc., Bio-Rad Laboratories Inc., Lonza, Promega Corporation, New England Biolabs, and Oxford Expression Technologies Ltd. Several M&As along with partnerships have been undertaken by these players to boost their presence in different regions.

Global Protein Expression Market Segmentation

Market Insight, by Expression Systems

·        Prokaryotic expression systems

·        Mammalian cell expression systems

·        Insect cell expression systems

·        Yeast expression systems

·        Other expression systems

Market Insight, by Applications

·        Therapeutic

·        Industrial

·        Research

Market Insight, by Product

·        Reagents

·        Competent cells

·        Expression vectors

·        Services

·        Instruments

Market Insight, by End Users

·        Pharmaceutical and biotechnological companies

·        Academic research

·        Contract research organizations

·        Others

Market Insight, by Region

·        North America Protein Expression Market

o   United States

o   Canada

o   Rest of North America

·        Europe Protein Expression Market

o   Germany

o   United Kingdom

o   France

o   Spain

o   Rest of Europe

·        Asia-Pacific Protein Expression Market

o   China

o   Japan

o   India

o   Australia

o   Rest of Asia-Pacific

·        Rest of World Protein Expression Market

Top Company Profiles

·        Thermo Fisher Scientific Inc.

·        Merck KGaA

·        GenScript Biotech Corporation

·        Agilent Technologies Inc.

·        Takara Bio, Inc.

·        Bio-Rad Laboratories Inc.

·        Lonza

·        Promega Corporation

·        New England Biolabs

·        Oxford Expression Technologies Ltd.