The very first works of Frank Davis and coworkers in the 70s generated the first commercial PEGylated form of protein drug, modified adenosine deaminase (ADA). Enzyme ADA is used to treat severe combined immunodeficiency disease (SCID) mainly in young adults. (resource from https://half-life-extension.creative-biolabs.com/pegylation-based-half-life-extension-service.htm)
The very first works of Frank Davis and coworkers in the 70s generated the first commercial PEGylated form of protein drug, modified adenosine deaminase (ADA). Enzyme ADA is used to treat severe combined immunodeficiency disease (SCID) mainly in young adults. (resource from https://half-life-extension.creative-biolabs.com/pegylation-based-half-life-extension-service.htm)
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